Marc-René de Voyer de Paulmy d'Argenson (13 December 1623, Blois - May 1700, Venice) seigneur d'Argenson et de Vueil-le-Mesnil, comte de Rouffiac, was a French knight, politician and diplomat.
A son of René de Voyer de Paulmy d'Argenson and of Hélène de La Font, he was made councillor to the Parlement de Normandie on 26 August 1642, was intendant subdelegate of his fathter in the elections at Saintes and Cognac on 1 November 1644, and in the généralité of Poitiers on 2 January 1646.
Made maître des requêtes on 4 August 1649, on the following 4 September he became conseiller d'État and replaced his father as French ambassador to the Venetian Republic, where he then lived until 28 November 1655. On 25 January 1654 the king of France elevated Rouffiac in Angoumois to the status of a county in Marc-René's favour. Marc-René obtained letters patent as honorary maître des requêtes on 14 February 1657. He was a friend of Jean-Louis Guez de Balzac.
On 8 May 1650 he married Marguerite Houlier de La Pouyade. They had 7 children :